Cedars-Sinai Guerin Children’s
Center for Developmental and Regenerative Biology

Our Team

David Traver, PhD

David Traver, PhD

Director, Center for Developmental and Regenerative Biology

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David performed his graduate work in the laboratory of Irving Weissman at Stanford University where he developed mouse models of myeloid leukemia and identified myeloid-restricted progenitor subsets. He then joined the laboratory of Leonard Zon at Harvard University where he characterized the cellular biology of the zebrafish hematopoietic system.

Since starting his own laboratory in 2004, David has received a Career Development Award from the National Institutes of Health, a New Faculty Award from the California Institute for Regenerative Medicine, and Scholar Awards from the March of Dimes Foundation, the American Society of Hematology, the Sidney Kimmel Foundation for Cancer Research, and the Leukemia and Lymphoma Society.

Most recently, David was awarded the Till and McCulloch Award in 2019 from the International Society for Experimental Hematology for his pioneering work on hematopoietic stem cell development.

Emily White

Emily White

Laboratory Manager

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Emily graduated from UC San Diego with a B.S. in Molecular and Cell Biology and a B.S. in Public Health: Epidemiology in 2024. As an undergraduate, she began her research experience studying the role of autophagy in muscle cell remodeling. Her interests in developmental and regenerative biology grew during a biotech internship at Organogenesis, and as Editor-in-Chief of Saltman Quarterly, UC San Diego’s undergraduate biological research journal. She joined the Traver Lab after a course on stem cells piqued her interest, and she aspires to pursue graduate studies. Outside the lab, she enjoys hiking, reading, and trying out new creative skills.

Postdoctoral Fellows

Po Yuan Chen, Ph.D.

Po Yuan Chen, Ph.D.

Postdoctoral Fellow

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Po-Yuan Chen is a postdoctoral researcher specializing in zebrafish models and hematopoietic stem cell (HSC) development. He earned his bachelor’s degree in Biomedical Sciences from Chang Gung University (CGU), Taiwan, and completed his Ph.D. in Basic Medical Sciences at National Cheng Kung University (NCKU), Taiwan. During his graduate studies, Chen focused on the toxicity of vitamin B6 supplementation during seizures, potential treatments for B6-induced toxicity, and the role of the B6 catalytic enzyme PNPO in zebrafish development.
In October 2022, Chen joined the Traver Lab, where he continues working with zebrafish to investigate the role of the Notch signaling pathway in HSC development. His research explores key processes such as the emergence, proliferation, and differentiation of hematopoietic stem cells, contributing to a deeper understanding of stem cell biology.
Lin Grimm, Ph.D.

Lin Grimm, Ph.D.

Postdoctoral Fellow

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Lin gazed upon her first developing zebrafish embryo during her bachelor studies in Freiburg, Germany. It did not take long until she got hooked by the wonders of developmental biology. Fascinated by how organs are formed, she learned how to model Parkinson’s disease in zebrafish in Prof. Dr. Wolfgang Driever’s lab and then finished her Master thesis in 2014, exploring the mechanisms of collective cell migration in Prof. Dr. Virginie Lecaudey’s lab.

She stayed with the fish as her favourite model organism but moved to Brisbane, Australia where she explored the molecular mechanisms of lymphatic vasculature development in Prof. Dr. Ben Hogan’s lab at the University of Queensland as her PhD project, which ended in 2020.

Just prior to the COVID lockdown, Lin helped relocate the lab to Melbourne and continued her work as a postdoctoral fellow now in the context of cancer research at the Peter MacCallum Cancer Center and in association with the University of Melbourne until 2021.

Switching gears to study haematopoiesis, Lin joined the Traver lab in 2022.

She enjoys her highly collaborative projects involving lineage tracking and cell line profiling in zebrafish and is also excited to be working on cellular reprogramming of human stem cells into hematopoietic stem cells.

Outside of work, Lin likes mingling with her lab members for some fun activities, she loves exploring the city trying out new things and living an active lifestyle including boxing, hiking, weight lifting, creative activities and much more.

Hung-Chi Tu, Ph.D.

Hung-Chi Tu, Ph.D.

Postdoctoral Fellow

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Hung-Chi Tu, Ph.D., is a dedicated researcher with a background in medical laboratory science and biotechnology. She earned her bachelor’s degree from the Department of Medical Laboratory Science and Biotechnology at National Cheng Kung University (NCKU) in Taiwan. Following her undergraduate studies, Hung-Chi worked as a medical technologist specializing in molecular diagnostics. She later pursued her Ph.D. at the Institute of Basic Medical Sciences at NCKU under the mentorship of Professor Tzu-Fun Fu. Her doctoral research focused on investigating the role of folate signaling in hematopoiesis, cardiovascular development, UV susceptibility, and melanocyte biology using zebrafish as a model organism.

In February 2020, Hung-Chi joined the Traver Lab at the University of California, San Diego, where she continues to explore her interests in hematology. Her current research examines the role of Notch signaling during the emergence of hematopoietic stem cells (HSCs). Additionally, she is working on generating transgenic zebrafish with fluorescently labeled Notch ligands to enable live imaging and tracking of ligand dynamics within cells.

Graduate Students

Jose Chacon, B.S.

Jose Chacon, B.S.

Doctoral Student

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Jose completed his undergraduate degree in Cell and Molecular Biology at California State University, Northridge (CSUN). He started his research experience studying neural crest cells in chick development under the mentorship of Dr. Crystal Rogers at CSUN. He later continued neural crest work at Caltech in Dr. Marianne Bronner’s lab, working under the mentorship of Dr. Erica Hutchins to study RNA-binding proteins in neural crest development. During his last year of undergrad, Jose also worked remotely as a research assistant in Dr. Rhiju Das’ lab at Stanford, where he worked to identify structured regions of the SARS-CoV-2 genome in a team effort to help aid therapeutic design.

Jose joined the Traver lab in 2022, where he continues his fascination with developmental biology. Now studying hematopoietic stem cells and their niche environment in zebrafish, while also conducting work with human pluripotent stem cells.

Outside of the lab, Jose enjoys playing basketball, soccer, spending time with family, and writing occasionally.

Julia Okrina, B.S.

Julia Okrina, B.S.

Doctoral Student

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Julia Okrina holds a Bachelor’s degree in Biology with a focus on Microbiology and Genetics from the University of Vienna. During her Bachelor’s thesis at the Max Perutz Labs, she worked with cardiac stem cells, investigating key signaling pathways and proteins involved in promoting heart regeneration. She is currently pursuing her Master’s degree in Molecular Biotechnology at the University of Applied Sciences FH Campus Vienna. In April 2025, she will join the Traver Lab for her Master’s thesis, supported by the Austrian Marshall Plan Foundation. Her work will focus on the development of hematopoietic stem cells from human pluripotent precursors, continuing her interest in regenerative biology and stem cell fate decisions.

Reanna Tariq, B.S.

Reanna Tariq, B.S.

Doctoral Student

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Reeanna first joined the Traver Lab after taking the Stem Cells and Regeneration course during her final quarter at UC San Diego, where she developed a strong interest in stem cell biology. She graduated in 2024 with a B.S. in Human Biology and a minor in Health Care–Social Issues. Currently, Reeanna is pursuing her Master of Public Health in Community Health Sciences at UCLA while continuing research in the Traver Lab alongside postdoctoral fellow Hung-Chi Tu. Her work focuses on genotyping transgenic zebrafish with fluorescent knock-in reporters to support investigations into the role of Notch signaling in hematopoietic stem cell development.

Before joining the lab, Reeanna held clinical and research roles focused on reproductive health and primary care, with a strong commitment to advancing health equity for underserved communities. Outside of the lab, she enjoys working out at the gym and exploring new matcha spots throughout Los Angeles.

Research Staff

 Carsten Hoeke

Carsten Hoeke

Research Staff

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In 2022, Carsten began his research journey in the Jacobsen Lab at UCLA/HHMI, where he worked on characterizing histone-protein complexes to identify their roles in epigenetic pathways using model Arabidopsis Thaliana. From 2022 to 2024, he joined Julie Law’s Lab at the Salk Institute, focusing on the inheritance of methylation patterns in the RNA-Directed DNA Methylation (RdDM) pathway.

Carsten’s passion for stem cell biology was sparked during his undergraduate studies at the University of California, San Diego, in Dr. Traver’s class. After earning a B.S. in General Biology with a Minor in Business Economics in 2024, he joined the Traver Lab full-time. Collaborating with post-doctoral fellow Lin Grimm, he now studies the early development of hematopoietic stem cells and their niche environments using Danio Rerio and human embryonic stem cells as model systems.

Jolene Nesnas

Jolene Nesnas

Research Staff

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Jolene Nesnas graduated from the University of California, San Diego with a Bachelor’s degree in Human Biology and a minor in Psychology. Her interest in stem cell research was sparked during her final year of undergrad after taking Dr. Traver’s Stem Cells and Regeneration course, which ultimately led her to join the Traver Lab in early 2025. Under the mentorship of postdoctoral fellow Po-Yuan Chen, she primarily explores the roles of different Notch ligands in the development of hematopoietic stem cells in zebrafish. In addition to her work in the lab, Jolene also works as a behavior technician, using Applied Behavior Analysis (ABA) therapy techniques to support young children. Outside of the lab, she enjoys spending time with friends and family, engaging in artistic pursuits, and traveling to explore new parts of the world.

Leilani Ramirez

Leilani Ramirez

Research Staff

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Leilani Ramirez holds a bachelor’s degree In Microbiology from Cal Poly SLO. She has spent time on research teams focusing on various projects including – medical entomology studying the effects of essential oils on bacterial pathogens within cockroaches, the development of a novel testing method for human respiratory viruses, and the microbiomes of deep-sea methane seep dwelling pycnogonids. Leilani joined the Traver Lab in March of 2025.

Richey Shi

Richey Shi

Research Staff

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Xuefan Shi (Richey) holds a B.S. in Cellular and Molecular Biology from San Diego State University (SDSU). He completed the Bridges to Stem Cell Research Internship Program through the California Institute for Regenerative Medicine (CIRM), a collaborative initiative between SDSU and UC San Diego (UCSD). During this internship, he focused on establishing a differentiation protocol for generating patient-specific and transplantable hematopoietic stem cells (HSCs) from human embryonic stem cells (hESCs) and induced pluripotent stem cells (hiPSCs).

In June 2024, Xuefan joined the Traver Lab, where he continues to investigate the generation of functional HSCs through modulation of WNT and NOTCH signaling pathways. His research aims to contribute to the development of alternative clinical transplantation approaches for treating acute myeloid leukemia (AML) and other blood disorders, with the goal of eliminating the need for donor matching and minimizing immune rejection.

Former Members

Julien Bertrand
Associate Professor, University of Geneva
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Cara Bickers
Associate Scientist, Fate Therapeutics
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Emerald Butko
Scientist, Advanced Cell Diagnostics
[email protected]

Clyde Campbell
Adjunct Assistant Professor, Iowa State University
[email protected]

Wilson Clements
Associate Member, St. Jude Children’s Research Hospital
[email protected]

Natasha Del Cid
Scientist, eBioscience
[email protected]

Tamar Dishon, Ph.D

Martin Distel
Group Leader, St. Anna Kinderkrebsforschung, Vienna
[email protected]

Sophia Espanola
Research Scientist, Vertex Pharmaceuticals
[email protected]

Raquel Espin Palazon
Assistant Professor, Iowa State University
[email protected]

Shai Eyal, Ph.D.

Stephanie Grainger
Assistant Professor, San Diego State University
[email protected]

Albert Kim
Scientist 2, 10X Genomics
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Isao Kobayashi
Assistant Professor, Kanazawa University
[email protected]

Yoonsung Lee
Investigator and Section Head, IBS, Korea
[email protected]

Kanako Lewis
Staff Scientist, Thermo Fisher Scientific
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Jessican Lin, B.S.

Gianncarlo Lugo
Scientist, CNRS, Toulouse
[email protected]

Jennifer Manegold
Medical Student, UCLA
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Karen Ong

Claire Pouget
Senior Scientist, Angiocrine Bioscience
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Dhiya Ram

Jenna Richter
Program Manager, University of Minnesota Medical School
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Pankaj Sahai-Hernandez

Buyung Santoso
Scientist, Ferring Research Institute
[email protected]

David Stachura
Associate Professor, CSU Chico
[email protected]

Michiel Van der Vaart
Assistant Professor, Leiden University
[email protected]

Bart Weijts
Senior Fellow, Hubrecht Institute
[email protected]

Valerie Wittamer
Associate Professor, Free University of Brussels
[email protected]

Clifford Wright, B.S.